MOLECULAR STUDY ALZHEIMER 3 - PRESENILIN 1 (COMPLETE SEQUENCING GENE PSEN1), WHOLE BLOOD

New Test in CIC Catalog

Test Code: 3917

Sample:	Whole blood - EDTA (5 ml)
Conservation:	Refrigerated
Method:	Sequencing Method
Set Up Days:	Daily
TAT (Days):	40 days
Information:
Alzheimer disease (AD) is characterized by dementia that typically begins with subtle and poorly recognized failure of memory and slowly becomes more severe and, eventually, incapacitating. Other common findings include confusion, poor judgment, language disturbance, agitation, withdrawal, and hallucinations. The typical clinical duration of the disease is eight to ten years, with a range from one to 25 years. About 25% of all AD are familiar of which about 95% is late-onset (after age 60-65 years) and 5% is early-onset (before age 65 years). Three forms of early-onset familial AD (EOFAD) caused by mutations in one of these genes (APP, PSEN1, PSNE2) are recognized. Mutations in PSEN2 are associated with Alzheimer disease type 4 (AD4) which accounts for less than 5% of all EOFAD.

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