Friday, April 26, 2024

STATUS OF IFI INFECTIOUS ANTIBODY REAGENTS

TESTS UNDER FOLLOW-UP WITH POSSIBLE CHANGES IN THE SHORT TERM


Temporarily discontinued test

Effective update from 29/04/2024

CODIGO LIS

DESCRIPCION

2497/2498/4418

IGG,M BARTONELLA HENSELAE AB

225 / 3536 / 1160

IGG,M,A CANDIDA ALBICANS AB

2278 / 3686 / 5581 / 5607

IGG,M,A GIARDIA LAMBLIA AB

   Find the record of the test by clicking here

IgE SPECIFIC ANTIBODIES FOR ZINC (c648), SERUM

Erased Test

Test code: 6293
Mnemonic code: C648

Effective update from 26/04/2024

Erased test due to discontinuation of the reagent manufacturing.

   Find the record of the test by clicking here

Thursday, April 25, 2024

INTOLERANCE 2

Temporarily discontinued Test

Test code: 7826
Mnemonic code: INTOL

Effective update from 25/04/2024

Temporary test suspension due to the temporary cessation of service by the supplier

   Find the record of the test by clicking here

Wellness Check

Temporarily Descontinued Test

Test code: 7813
Mnemonic code: NHBA

Effective update from 25/04/2024

Temporary test suspension due to the temporary cessation of service by the supplier

   Find the record of the test by clicking here

Leptospira interrogans IgG antibodies, CSF

Temporarily discontinued Test

Test code: 5450, 5451
Mnemonic code: LEPGLC, LEPMCR

Effective update from 25/04/2024

Temporarily discontinued tests due to discontinuation in reagent supply.

                                        Find the record of the test by clicking here

HLA-B27 genotype, total blood

Description, Method, Result Format and Reference values Modification

Test code: 2909
Mnemonic code: B27

Effective update from 06/05/2024




PREVIOUS

NEW
        
Description: HLA-B27 genotype, total blood


Method: Real-Time PCR



Result format:  R1  Result



Reference Values:
Negative
     
Technique: DNA extraction from whole blood and subsequent amplification by real-time PCR (commercial CE-IVD method) of the HLA-B*27 gene, associated with seronegative spondyloarthropathies, and a control gene.
     
Explanatory note: It is present in approximately 7% of Caucasian individuals and in 89% of patients with ankylosing spondylitis. It can also be positive in 42% of patients with juvenile rheumatoid arthritis and in 79% of patients diagnosed with Reiter's syndrome.
* Source: PNT, Insert
























 Version of Test: 12
     



Description: HLA-B27 GENOTYPE, WHOLE BLOOD


Method: Multiplex PCR/Real-Time PCR



Result format:  R1  Sample
                R2  Result
  
       
Reference Values:
Interpretation
HLA-B27 variant is found in more than 90% of patients with ankylosing spondylitis (Morbus Bechterew). It is also present in 42% of patients with juvenile rheumatoid arthritis and in 79% of Reiter's syndrome patients. However, it is also found in 8-10% of general population, so having the HLA-B27 gene does not mean that a person suffers or will suffer from ankylosing spondylitis.
The disease mainly affects men (3 times more common than women) between the ages of 20 and 40 and it is characterized by inflammation of spine (spondylitis), large joints, fingers and feet, leading to stiffness and pain. Eye inflammation is also characteristic.
This report should be evaluated by a specialist in the context of all available clinical and family information in conjunction with other laboratory findings. Genetic counselling is recommended.

Test method
DNA extraction followed by real-time PCR amplification (CE-IVD commercial method) of  HLA-B*27 gene, associated with Behçet's disease predisposition, and a control gene.

Test limitations
Variants other than those studied are not analyzed.
Normal/polymorphic genomic variation in the patient may interfere with variant detection in the sample.

References
Caffrey MF et al. (1973) Nature. 242:121
Schlosstein L et al. (1973). N Engl J Med.
Agrawal P et al. (2024). Cureus 16(1)
 


      Version of Test: 13
     

      Find the record of the test by clicking here

LEPTOSPIRA INTERROGANS IgG and IgM ANTIBODIES SERUM

Temporarily discontinued Test

Test code: 3114, 3115, 5218
Mnemonic code: LEPTG, LEPT

Effective update from 25/04/2024

Temporarily discontinued tests due to discontinuation in reagent supply.

   Find the record of the test by clicking here

Wednesday, April 24, 2024

Cloroquine, serum

Reference values Modification

Test code: 5592
Mnemonic code: CLQUI

Effective update from 06/05/2024




PREVIOUS

NEW
        
      0.01 - 0.4 mg/L
      LOD and LOQ: 0.005 mg/L
     
     
      Version of Test: 15
     

        
      0.02 - 0.5 mg/L   
         
         
     
      Version of Test: 16
     

   Find the record of the test by clicking here

Monday, April 22, 2024

IMPORTANT COMMUNICATION: STATUS OF IFI INFECTIOUS ANTIBODY REAGENTS

 IMPORTANT COMMUNICATION: STATUS OF IFI INFECTIOUS ANTIBODY REAGENTS

Dear colleagues and collaborators, 

We inform you about an important update regarding the availability of certain tests and reagents for the Indirect Immunofluorescence (IFI) technique that we have been performing for the detection of infectious disease antibodies.

Recently, we have experienced changes in our supply chain due to circumstances beyond our control and unfortunately, our official supplier of reagents for the IFI technique has permanently ceased production of the reagents.

As a result, some of the tests we offer will be temporarily unavailable or may experience changes in availability. 

We would like to assure you that we are working diligently to minimize any inconvenience this may cause and are exploring all available options to restore the availability of these tests as soon as possible.

We would therefore like to keep you updated on the current situation arising from this event;

TEMPORARILY ERASED TESTS

TEST CODE

DESCRIPTION

OBSERVATIONS

938/ 2032/4715

RESPIRATORY SYNCYTIAL VIRUS IGG,M ANTIBODIES

Pending results will be issued on time

1009/ 1010/4699

INFLUENZA A VIRUS IGG,M ANTIBODIES

Pending results will be issued on time

2040/ 2041

INFLUENZA B VIRUS IGG,M ANTIBODIES

Pending results will be issued on time

3076

INFLUENZA (A+B) VIRUS IGM ANTIBODIES

Pending results will be issued on time

7670/ 3106/ 3229

BORDETELLA PARAPERTUSSIS IGG,M,A ANTIBODIES

Pending results will be issued on time

2064/ 2065/ 2375

BORDETELLA PERTUSSIS IGG,M,A ANTIBODIES

Pending results cannot be issued in a timely manner until test reactivation, for emergencies contact the laboratory.

TESTS UNDER FOLLOW-UP WITH POSSIBLE CHANGES IN THE SHORT TERM

TEST CODE

DESCRIPTION

OBSERVATIONS

2497/ 2498/4418

BARTONELLA HENSELAE IGG,M ANTIBODIES

Pending results will be issued on time

225/ 3536/ 1160

CANDIDA ALBICANS IGG,M,A ANTIBODIES

Pending results will be issued on time

3114/ 3115

LEPTOSPIRA INTERROGANS IGG,M ANTIBODIES

Pending results will be issued on time

4276/ 4275/ 7662

VARICELA ZOSTER IGG,M,A ANTIBODIES

Pending results will be issued on time

7686/ 7687/ 2095/ 7323/ 7324

EPSTEIN BARR VCA IGG,M,A ANTIBODIES

Pending results will be issued on time

2217/ 2218/ 4222/ 4223

IGG,M ANTIBODIES VIRUS HERPES TIPO 6

Pending results will be issued on time

2397

LEGIONELLA PNEUMOPHILA IGA ANTIBODIES

Pending results will be issued on time

2672/ 2671/ 7684/ 7685

COXSACKIE VIRUS A9 IGG,M ANTIBODIES

Pending results will be issued on time

2048/ 2047/ 7681/ 7682

COXSACKIE VIRUS B16 IGG,M ANTIBODIES

Pending results will be issued on time

2278/ 3686/ 5581/5607

GIARDIA LAMBLIA IGG,M,A ANTIBODIES

Pending results will be issued on time

4711/ 4712/ 4714/ 4713

ADENOVIRUS IGG,M ANTIBODIES

Pending results will be issued on time

7310/ 7309

PARAINFLUENZA 1 IGG,M ANTIBODIES

Pending results will be issued on time

7318/ 7319

PARAINFLUENZA 2 IGG,M ANTIBODIES

Pending results will be issued on time

7320/ 7321

PARAINFLUENZA 3 IGG,M ANTIBODIES

Pending results will be issued on time


We understand that this may raise concerns and want to assure you that we are committed to maintaining the quality and integrity of our products.

We are taking all necessary steps to mitigate any impact on your clinical practice and are available to provide the necessary support during this transition period.

Please do not hesitate to contact us for any further clarification.

Yours sincerely,



Thursday, April 18, 2024

MOLECULAR STUDY GENOTYPE MHC-B (LOW RESOLUTION), WHOLE BLOOD

Reference values Modification

Test code: 3867
Mnemonic code: Does not apply

Effective update from 22/04/2024




PREVIOUS

NEW
        
      *This result express typification for
      every allele of the correspondient loci.
     
      Susceptibility:
      . Beheçet disease (B*51)
      . Subacute thyroiditis (B*35)
      . Carbamazepine susceptibility (B*15:02)
     
     
      Version of Test: 4
     

 
   *This result express typification for every allele of the correspondient loci.    
         
         
         
         
         
         
     
      Version of Test: 5
     


   Find the record of the test by clicking here

MOLECULAR STUDY GENOTYPE MHC-A (LOW RESOLUTION), WHOLE BLOOD

Reference values Modification

Test code: 3930
Mnemonic code: Does not apply

Effective update from 22/04/2024




PREVIOUS

NEW
        
      *This result express typification for
      every allele of the correspondient loci.
     
      Susceptibility:
      . Uveitis type Birdshot(A*29)
      . Carbamazepine susceptibility (A*31:01)
     
     
      Version of Test: 4
     


   *This result express typification for every allele of the correspondient loci.
       
               
 
        
         
     
      Version of Test: 5
     


   Find the record of the test by clicking here

IgE SPECIFIC ANTIBODIES FOR IODINE (c616)

Erased Test

Test code: 6320
Mnemonic code: C616

Effective update from 22/04/2024

Erased test due to discontinuation of the reagent manufacturing.

   Find the record of the test by clicking here

Rotavirus IgM antibodies, Serum

Discontinued Temporarily Test

Test code: 5100
Mnemonic code: ROTAM

Effective update from 19/04/2024

Temporarily discontinued test due to discontinuation in reagent supply.

   Find the record of the test by clicking here

BORDETELLA PERTUSSIS (WHOOPING COUGH) IgA, IGg and IgM ANTIBODIES, SERUM

Temporarily discontinued Test

Test code: 2375, 2064, 2065
Mnemonic code: BORDA, BORDG, BORDM

Effective update from 19/04/2024

Temporarily discontinued tests due to discontinuation in reagent supply.

   Find the record of the test by clicking here

Wednesday, April 17, 2024

Salicilyc Acid, Serum

Description, Units and Reference Modification

Test code: 256
Mnemònic code: AASA

Effective update from 29/04/2024




PREVIOUS

NEW
        
       Description: Salicilyc Acid, Serum

       Units: µg/mL 

       Reference Values
       THERAPEUTIC LEVEL (Anestesia-Analgesic): 20-100 µg/mL
      (Antiinflamatory) : 100-300 µg/mL
      TOXIC LEVEL: Greater than 300 µg/mL
      * Fuente: PNT, Insert
     
    


     
     
      Version of Test: 7
     

        
      Description: ACETYLSALICYLIC ACID, SERUM

      Units: mg/L

      Reference Values:
      Therapeutic range: 20 - 200 mg/L
      Toxicity: Greater than 300        *Source: Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020 
         
         
             
     
      Version of Test: 8
     

   Find the record of the test by clicking here

Friday, April 12, 2024

ANTI POLIOVIRUS ANTIBODIES, SERUM

Temporarily Discontinued Test

Test code: 3178
Mnemonic code: POLIO

Effective update from 15/04/2024

Temporarily discontinued test due to discontinuation in reagent supply.

   Find the record of the test by clicking here

IgE SPECIFIC ANTIBODIES FOR IODINE (c616)

Temporarily Discontinued Test

Test code: 6320
Mnemonic code: C616

Effective update from 15/04/2024

Temporarily discontinued test due to discontinuation in reagent supply.


                         Find the record of the test by clicking here

CANNABIS CONFIRMATION (LC-MS/MS), HAIR

Units and Reference values Modification

Test code: 4384
Mnemonic code: CANNP

Effective update from 22/04/2024




PREVIOUS

NEW
        
      
      Units: ng/mg


      Reference Values:
      Cut off values recommended by EDWTS, 2022: 0.05 ng/mg hair
     
      EDWTS: European Workplace Drug Testing Society, 2022)
      

     
      Version of Test: 5
     

        
         
      Units: pg/mg   
         
         
      Reference Values:
      THC Cut-off value: 60 pg/mg







      Version of Test: 6
     

   Find the record of the test by clicking here