Friday, July 28, 2017

CAFFEINE, SERUM

Reference values, Conservation of the Sample, and Delivery Time Modification

Test code: 1536

Effective update from 31/07/2017




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5- 20 mg/L
(LOD and LOQ: 1 mg/L)

Premature babies:
  - The therapeutic zone comonly admitted is from 5 to 20 mg/L.
  - However, concentrations between 15mg/L and 20mg/L show a more favorable efficiency/toxicity ratio 

(Gal P.J Pediatr Pharmacol Ther 2007 VOL 12 NÂș4).
     
Sample: Serum (1 mL) Frozen      

Delivery term: 6 days
     

        
2 - 10 mg/L     
         
         
         
(Schulz et al. Critical Care 2012, 16:R136
http://ccforum.com/content/16/4/R136)   
         
         
         
    


Sample: Serum (1 mL) Refrigerated    
     
Delivery term: 5 days
     

   Find the record of the test by clicking here

Restrictions for samples reception


We inform you that for 15th August festivity, no samples will be accepted for:


NEOBONA ADVANCE PLUS TEST AND HARMONY

We can not receive samples from 11th-15th August, inclusive


MELISA TEST

We can not receive samples from 7th-15th August, inclusive.


AUTOLOGOUS SERUM

We can not receive samples on 15th August

Thursday, July 27, 2017

Cocaine confirmation (with chromatogram), urine

Reference values Modification

Test code: 5254

Effective update from 31/07/2017




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NEW
        
      Cocaine:
      Cut-off: 25 ng/mL
      Measuring uncertainty: 5 ng/mL
     
      Benzoilecgnonine:
      Cut-off: 25 ng/mL
      Measuring uncertainty: 5 ng/mL
     
      In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the cut-off value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range.
     

     
      Cocaine:
      Quantification limit: 25 ng/mL
      Measuring uncertainty: 3,3 ng/mL
     
      Benzoilecgnonine:
      Quantification limit: 25 ng/mL
      Measuring uncertainty: 3,9 ng/mL
     
      In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the quantification limit value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range.        
         
         
         
         
         
         
         
         

   Find the record of the test by clicking here

Cocaine (confirmation), urine

Reference values Modification

Test code: 2550

Effective update from 31/07/2017




PREVIOUS

NEW
        
      Cocaine:
      Cut-off: 25 ng/mL
      Measuring uncertainty: 5 ng/mL
     
      Benzoilecgnonine:
      Cut-off: 25 ng/mL
      Measuring uncertainty: 5 ng/mL
     
      In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the cut-off value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range.
     

        
      Cocaine:
      Quantification limit: 25 ng/mL
      Measuring uncertainty: 3,3 ng/mL
     
      Benzoilecgnonine:
      Quantification limit: 25 ng/mL
      Measuring uncertainty: 3,9 ng/mL
     
      In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the quantification limit value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range.    
         
         
         
         
         
         
         
         
         

   Find the record of the test by clicking here

HISTIDINE 3 METHYL, PLASMA

Reference values, Sample and Delivery Time Modification

Test code: 1103

Effective update from 28/07/2017




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      2 - 9 ”mol/L
      LOD: <0.01 ”mol/L

     


Sample: Plasma (Lithium Heparin) (1 mL). Frozen.      

      Delivery term: 10 days
     

               
Premature and Adult: Less than 5 Â”mol/L 

Newborns: 5 - 23 Â”mol/L



Sample: Plasma (EDTA) (1 mL). Frozen.  
         
     
      Delivery term: 17 days
     

   Find the record of the test by clicking here

Familial Hypertrophic Cardiomyopathy, panel (27 genes) NGS, whole blood

Description Modification

Test code: 1247

Effective update from 28/07/2017



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NEW

Familial Hypertrophic Cardiomyopathy, panel (27 genes) NGS, whole blood
     
ACTC1, GLA,  MYBPC3, MYH7, MYL2,  MYL3,  PRKAG2, PTPN11, TNNI3, TNNT2, TPM1, ACTN2, AGL, ANKRD1, BRAF, CALR3, CASQ2, CAV3, CRYAB, CSRP3, CTF1, DES, DTNA, FHL1, FXN, GAA, JPH2

Familial Hypertrophic Cardiomyopathy, panel (41 genes) NGS, whole blood
         
ALPK3, ACTC1, ACTN2, AGL, ANKRD1, BAG3, CALR3, CASQ2, CAV3, COX15, CRYAB, CSRP3, DES, FLNC, GAA, GLA, JPH2, LAMP2, LDB3, MYBPC3, MYH6, MYH7, MYL2, MYL3, MYLK2, MYO6, MYOZ2, MYPN, NEXN, PDLIM3, PLN, PRKAG2, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TTN, TTR, VCL
   Find the record of the test by clicking here

Dilated Cardiomyopathy, panel (59 genes) NGS, whole blood

Description Modification

Test code: 4735

Effective update from 28/07/2017




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Dilated Cardiomyopathy, panel (59 genes) NGS, whole blood

ACTC1, BAG3, DES, DMD, DSP, FLNC, LMNA, MYBPC3, MYH7, PKP2, PLN, RBM20, TAZ, TNNC1, TNNI3, TNNT2, TPM1, TTN, ABCC9, ACTA1, ACTN2, ALMS1, ANKRD1, CAV3, CRYAB, CSRP3, DNAJC19, DOLK, DSC2, DSG2, EMD, EYA4, FHL2, FKRP, FKTN, FOXD4, GAA, GATA4, GATA6, GATAD1, GLB1, HFE, JUP, LAMA2, LAMA4, LAMP2, LDB3, MURC, MYH6, MYL2, MYL3, MYOT, MYPN, NEBL, NEXN, PSEN1, PSEN2, RAF1, RYR2, SCN5A, SGCD, SLC22A5, TBX20, TCAP, TMEM43, TMPO, TTR, TXNRD2, VCL

        
Dilated Cardiomyopathy, panel (67 genes) NGS, whole blood  

ABCC9, ACTC1, ACTN2, ANKRD1, BAG3, CAV3, CSRP3, CRYAB, CTF1, DES, DMD, DNAJC19, DOLK, DSC2, DSG2, DSP, EMD, EYA4, FBXO32, FHL2, FKTN, FKRP, FLNC, FOXD4, GATA4, GATAD1, HCN4, ILK, JUP, LAMA4, LAMP2, LDB3, LMNA, MYBPC3, MYH6, MYH7, MYPN, NEBL, NEXN, PDLIM3, PKP2, PLEKHM2, PLN, PRDM16, PSEN1, PSEN2, RAF1, RBM20, RYR2, SCN5A, SDHA, SGCD, SYNE1, SYNE2, SLC22A5, TAZ, TBX20, TCAP, TMPO, TNNC1, TNNI3, TNNT2, TPM1, TTN, TTR, TXNRD2, VCL
   Find the record of the test by clicking here

Dilated Cardiomyopathy, panel (18 genes) sequencing, whole blood

Description Modification

Test code: 3898

Effective update from 28/07/2017



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NEW
        
Dilated Cardiomyopathy, panel (18 genes) sequencing, whole blood

ACTC1, BAG3, DES, DMD, DSP, FLNC, LMNA, MYBPC3, MYH7, PKP2, PLN, RBM20, TAZ, TNNC1, TNNI3, TNNT2, TPM1, TTN

        
Dilated Cardiomyopathy, panel (30 genes) sequencing, whole blood

ACTC1, ACTN2, ANKRD1, AG3,CSRP3, DES, DMD, DSG2, EYA4, LDB3, LMNA, MYBPC3, MYH6,  MYH7, NEXN, PLN, PSEN1, PSEN2, RBM20, SCN5A, SGCD,TAZ, TCAP,TMPO, TNNC1, TNNI3, TNNT2, TPM1, TTN, VCL   

   Find the record of the test by clicking here

HISTIDINE 3 METHYL, PLASMA

Erased test

Test code: 1103

Effective update from 28/07/2017




         

   Find the record of the test by clicking here

Thursday, July 20, 2017

OPIATES- CONFIRMATION, URINE

Reference values and Delivery Time Modification

Test code: 2543

Effective update from 25/07/2017




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      Negative:
      Codeine and Morphine: Less than 300 ng/mL. LOD: < 10 ng/mL
      6-MAM (6-Monoacetylmorphine): Less than 10 ng/mL.LOD:< 1 ng/mL
     
      EWDTS 2011 (European Workplace Drug Testing Society).
     
     
     
      Delivery term: 12 days
     

             
 Morphine:
    Quantification limit:     25 ng/mL
    Measurement uncertainty: 5.4 ng/mL

 6-monoacetyl morphine (6AM):
    Quantification limit:     10 ng/mL
    Measurement uncertainty:   2 ng/mL

 Codeine:
    Quantification limit:      25 ng/mL
    Measurement uncertainty : 4.2 ng/mL   
       
         
 In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the quantification limit value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range. 

   Delivery term: 3 days
     

   Find the record of the test by clicking here

Opiates confirmation (with chromatogram), urine

Reference values and delivery time Modification

Test code: 5256

Effective update from 25/07/2017




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      Negative:
      Codeine and Morphine: Less than 2000 ng/mL
      6-MAM (6-Monoacetylmorphine): Less than 10 ng/mL.
      (SAMSHA:The Substance Abuse and Mental Health Services Administration).
     
     
      Delivery term: 12 days

 Morphine:
    Quantification limit:     25 ng/mL
    Measurement uncertainty: 5.4 ng/mL

 6-monoacetyl morphine (6AM):
    Quantification limit:     10 ng/mL
    Measurement uncertainty:   2 ng/mL

 Codeine:
    Quantification limit:      25 ng/mL
    Measurement uncertainty : 4.2 ng/mL 

  In the received sample all of the indicated substances have been analyzed. The following positivity criterion has been used: when the concentration of the substances is over or equal the quantification limit value plus the value of test uncertainty, the result is Positive. In opposite case the result is Negative. The laboratory has a measurement uncertainty across the entire working range.  

   Delivery term: 3 days
  
   Find the record of the test by clicking here

Tuesday, July 18, 2017

ETHANOL, URINE

Reference values and Delivery Time Modification

Test code: 905

Effective update from 19/07/2017




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NEW
        
      Up to 0.01 g/L


  

   The urine alcohol analysis indicates the presence of ethanol in the body but there is no direct relationship between this value and the blood content. For confirmation of positive values in sobriety checks for drivers is required the ethanol analysis in whole blood.

      Bibliography: F.I Prada et al, Annals of the Spanish Royal Society of Chemistry (2003).
      * Fuente: Valores Bibliograficos
     
      Delivery term: 3 days
     

        
         
   Uncertainty (to 0,05 g/L): 0.01 g/L

 Limit of quantification: 0.05 g/L  
  
 The urine alcohol analysis indicates the presence of ethanol in the body but there is no direct relationship between this value and the blood content. For confirmation of positive values in sobriety checks for drivers is required the ethanol analysis in whole blood.

      Bibliography: F.I Prada et al, Annals of the Spanish Royal Society of Chemistry (2003).
      * Fuente: Valores Bibliograficos
     
      Delivery term: 4 days
   Find the record of the test by clicking here