CAFFEINE, SERUM

Reference values, Conservation of the Sample, and Delivery Time Modification

Test code: 1536

Effective update from 31/07/2017

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5- 20 mg/L (LOD and LOQ: 1 mg/L) Premature babies:   - The therapeutic zone comonly admitted is from 5 to 20 mg/L.   - However, concentrations between 15mg/L and 20mg/L show a more favorable efficiency/toxicity ratio  (Gal P.J Pediatr Pharmacol Ther 2007 VOL 12 Nº4).       Sample: Serum (1 mL) Frozen       Delivery term: 6 days	2 - 10 mg/L                                    (Schulz et al. Critical Care 2012, 16:R136 http://ccforum.com/content/16/4/R136)                                       Sample: Serum (1 mL) Refrigerated           Delivery term: 5 days

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