Test code: 3429
Effective update from 11/05/16
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Isocyanates (metabolites: 2,4-TDA and 2,6-TDA), urine
People exposed to TDI (toluene diisocyanate)
Indicative way, at the end of the day labor
2,4-TDA (toluene 2,4-diamine): 2.8 - 9.6 mg/g creatinine
2,6-TDA (toluene diamine-2,6): 5.6 - 16.6 mg/g creatinine
The relationship between urinary concentration of TDA and health effects is not established, so these values are useful only as indicators of level of exposure
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Isocyanates (metabolites: HDA, 2,4-TDA, 2,6-TDA and MDA), urine
People exposed to HDI (hexamethylene diisocyanate 1,6)
Indicative biological limit value at the end of the workday
HDA (1,6-hexamethylene diamine): 17.5 to 52.6 mcg/g creatinine
People exposed to TDI (toluene diisocyanate)
Indicative biological limit value at the end of the workday
2,4-TDA (toluene diamine-2,4): 2.8 to 9.6 mcg/L
2,6-TDA (toluene diamine-2,6): 5.6 to 16.6 mcg/L
People exposed to MDI (4,4-methylene diphenylisocyanate)
biological limit value (BLW-DFG) at the end of the workday
MDA (4,4-methylene dianiline): 10.0 mcg/L
Amines are analyzed metabolites appear in the urine of people exposed to the corresponding diisocyanate (HDI, TDI, MDI).
The relationship between urinary concentration of HDA and TDA and health effects is not established, so these values are only useful as indicators of level of exposure.
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