Prostate Cancer (PCA3) screening, urine

Reference values Modification

Test code: 1318

Effective update from 31/10/2018

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The PCA3 Score is intended for use in conjunction with standard-of-care diagnostic algorithms as and aid in the diagnosis of prostate cancer. A PCA3 Score greater or equal to 35 indicates an over-expression of PCA3 mRNA with an increased probability of a positive repeat biopsy than a PCA3 Score < 35 and an active surveillance with a prostatic biopsy is appropriate. The PCA3 Score cut-off of 35 provides the optimal balance between sensitivity (64%) and specificity (76%).

The PCA3 Score is intended for use in conjunction with standard-of-care diagnostic algorithms as and aid in the diagnosis of prostate cancer. A PCA3 Score greater or equal to 25 indicates an over-expression of PCA3 mRNA with an increased probability of a positive repeat biopsy than a PCA3 Score < 25 and an active surveillance with a prostatic biopsy is appropriate. The PCA3 Score cut-off of 25 provides the optimal balance between sensitivity (64%) and specificity (76%).

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