PIK3CA (Exons 10, 21) Diagnosis, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 7361

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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PIK3CA (Exons 10, 21) Monitoring, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 7359

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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KRAS (codons 12, 13 and 61) Monitoring ,ONCOinBLOOD (Cell-free DNA detection), plasma and serum

Method Modification

Test code: 5569

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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EGFR (exons 19 and 21 + T790M mutation) Monitoring, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 5568

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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EGFR (exons 19 and 21 + T790M mutation) Diagnosis, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 5074

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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BRAF (V600E, V600K Mutations) Monitoring, ONCOinBLOOD (Cell-free DNA detection), plasma and serum

Method Modification

Test code: 5570

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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BRAF (Mutations V600E, V600K) Diagnosis, ONCOinBLOOD (Cell-free DNA detection), plasma and serum

Method Modification

Test code: 5073

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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EML4-ALK Translocation Monitoring, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 7357

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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EML4-ALK Translocation Diagnosis, ONCOinBLOOD (Cell-free DNA detection), serum and plasma

Method Modification

Test code: 7356

Effective update from 29/12/2017

PREVIOUS	NEW
Method: Real-Time PCR	Method: 5 'Nuclease PCR assay combined with PNA probes

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IgE SPECIFIC ANTIBODIES FOR AMOXICILLIN (c6)

Method Modification

Test code: 899

Effective update from 29/12/2017

PREVIOUS	NEW
Method: ImmunoCAP	Method: Chemiluminescence

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BORRELIA BURGDORFERI (LYME DISEASE) IgG / IgM ANTIBODIES, SERUM

Erased test

Test code: 5602

Effective update from 29/12/2017

ALTERNATIVE TESTS:

- 7582 - BORRELIA  IgM ANTIBODIES (CONFIRMATORIO) WESTERN-BLOT, SERUM
- 7583 - BORRELIA  IgG ANTIBODIES (CONFIRMATORIO) WESTERN-BLOT, SERUM

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GRAM STAIN

Erased test

Test code: 809

Effective update from 27/12/2017


This test is canceled as an individual test, it is reported within the microbiological culture.

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Polyomavirus BK/JC (PMV) DNA, biological sample

Reference values (note) Modification

Test code: 2727

Effective update from 29/12/2017

PREVIOUS	NEW
Not detected.             * This technique has 95% Sensitivity and 97% Specificity.       * Limit of detection: 600 copies/mL (only for JCV)	Not detected.          * The analytical sensitivity for the detection of DNA Polyomavirus JC is 2500 copies/ml * The analytical sensitivity for the detection of DNA Polyomavirus BK is 1500 copies/ml

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Polyomavirus BK/JC (PMV) DNA, total blood

Erased test

Test code: 4057

Effective update from 29/12/2017

ALTERNATIVE TESTS:

- 2727 - Polyomavirus BK/JC (PMV) DNA, biological sample

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Human Immunodeficiency Virus type 1 (HIV-1) protease, reverse transcriptase genotype, integrase (PR, RT, IN), whole blood

Delevery time Modification

Test code: 5251

Effective update from 27/12/2017

PREVIOUS	NEW
Delivery term: 20 days	Delivery term: 22 days

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CHLORAZEPAM- SERUM

Description, Reference values and Delivery time Modification

Test code: 3035

Effective update from 27/12/2017

PREVIOUS	NEW
CHLORAZEPAM- SERUM      Therapeutic level         : 0.2 - 1.0   µg/mL.     Sedative action      : 0.09 - 0.20 µg/mL.     Anticonvulsive action:  0.6 - 1.50 µg/mL. Toxic levels:     Sedative action      :   > 1.0     µg/mL.     Anticonvulsive action:   > 2.0     µg/mL. Delivery term: 20 days	CHLORAZEPAM (NORDIAZEPAM)- SERUM          Therapeutic level :     Sedative action         : 0.09 - 0.20 µg/mL.     Anticonvulsive action:  0.6  - 1.50 µg/mL. Toxic levels:     Sedative action         :       > 1.0     µg/mL.      Anticonvulsive action:       > 2.0     µg/mL. * Clorazepate is assayed as nordiazepam Delivery term: 8 days

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Human Immunodeficiency Virus type 1 (HIV-1) protease, reverse transcriptase genotype (PR, RT), plasma

Method and Delivery time Modification

Test code: 2765

Effective update from 22/12/2017

PREVIOUS	NEW
Method: Sequencing Method Delivery term: 15 days	Method: Next Generation Sequencing (NGS) Delivery term: 17 days

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ACETOACETATE, URINE

Erased test

Test code: 1524

Effective update from 22/12/2017

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VITAMIN A (RETINOL), SERUM

Reference values Modification

Test code: 417

Effective update from 21/12/2017

PREVIOUS	NEW
1 - 6 years: 0.2 - 0.4 mg/L       7 - 12 years: 0.26 - 0.49 mg/L       13 - 17 years: 0.26 - 0.72 mg/L       >18 years : 0.30 - 0.80 mg/L             * Source: Tiezt Reference Information for the Clinical Laboratory William L. Roberts, M.D., Ph.D., Gwendolyn A.McMillin, Ph.D.,D.A.B.C.C.(C.C.,T.C.), Carl A.Burtis, Ph.D.,and David E. Bruns, M.D.       * Fuente: Valores Bibliograficos	1 -  6 years: 0.20 - 0.40 mg/L   7 - 12 years: 0.26 - 0.49 mg/L  13 - 19 years: 0.26 - 0.72 mg/L     > 19 years: 0.30 - 0.80 mg/L                   * Source: Burtis C A, Ashwood, ER. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Bruns DE, Eds, Elsevier Saunders 2006; p.2302

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VITAMIN E (ALPHA TOCOPHEROL), SERUM

Reference values Modification

Test code: 419

Effective update from 21/12/2017

PREVIOUS	NEW
5 - 20 mg/L * Fuente: PNT, Insert	0 - 12 years: 3.0 -  9.0  mg/L 13 - 16 years: 6.0 -  9.9  mg/L    > 16 years: 5.2 - 18.1  mg/L    * Source: Burtis C A, Ashwood, ER. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Bruns DE, Eds, Elsevier Saunders 2006; p.2302

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