CHRONIC LYMPHATIC LEUKEMIA (SOMATIC HYPERMUTATIONS) - IGH - A. FRAGMENTS + SANGER

New Test in NOÛS Catalog

Test Code: 8662

Sample:	Tissue
Conservation:	Room temperature
Method:	Cleave Assay + Sanger Sequencing
Set Up Days:	Daily
Delivery term:	17 days
Information:
Lymphoid neoplasms are monoclonals and in the great majority of these proliferations the rearrangement of the genes of the Igs and of the RCT precedes the malignant transformation (with the exception of some proliferations of very immature cells). Consequently, all the cells derived from the same malignant stem cell will share a rearranged DNA in similar form and will express the same receptors (an identical Ig or RCT). For this reason, the analysis of the Igs or of the RCT by means of the PRC technique will allow us to detect clonality of populations of lymphoid B or T cells. OTHER TESTS IN CATALOGUE 2866, 257, 2751

   Find the record of the test by clicking here