Test code: 4169
Mnemonic code: FLUCO
Effective update from 21/05/2024
Effective update from 21/05/2024
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Sample (Only National): Frozen Serum Method: High Performance Liquid Chromatography Reference Values: - Oral administration: An indicative serum concentration of the order of 5, 8, and 10 mg/L respectively are obtained after oral administration of 200, 300, and 400 mg of Fluconazole per day (In an state of equilibium, i.e. at least 5 days after the start or modification of treatment). - IV administration: A maximum serum concentration of 2,5 mg/l is obtained after IV administration of 100 mg of Fluconazole in a single dose. LOD : 0.5 mg/L LOQ : 0.5 mg/L *Source: PNT, Insert Delivery term: 12 days Version of Test: 7 | Sample (Only National): Refrigerated serum (7 days stability)(*) (*)Serum Tube without separating gel Method: Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) Reference Values: Therapeutic range: 2 - 15 mg/L Toxicity: Greater than 20 mg/L *Source:Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020 Delivery term: 6 days Version of Test: 8 |
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