MOLECULAR STUDY SLC6A3 (DAT1) GENE 3´UTR POLYMORPHISM WHOLE BLOOD

New Test in CIC Catalog

Test Code: 4175

Sample:	Whole blood - EDTA (5 ml)
Conservation:	Refrigerated
Method:	Tri-Primer Polymerase Chain Reaction (TP-PCR)
Set Up Days:
Plazo de Entrega:	32 days
Information:
Differences in the dopamine and serotonin systems have been suggested as potential factors underlying interindividual variability in risk taking and in brain activation during the processing of feedback. The human dopamine transporter (DAT1) gene contains a variable number of tandem repeats (VNTR) in its 3?-untranslated region (UTR). The 9-repeat allele of the dopamine transporter (DAT) gene has been associated with increased striatal dopamine levels, and has been found to be related to increased sensitivity to reward. It is studied in relation with it´s possible implication with attention-deficit/hyperactivity disorder, risk taking behaviors, and various others neuropsychiatric disorders.
Links:
PLOS ONE- DAT1 Polymorphism Is Associated with Risk Taking in the Balloon Analogue Risk Task (BART)
The Pharmacogenomics Journal - The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression
OMIM Entry - - 126455 - SOLUTE CARRIER FAMILY 6 (NEUROTRANSMITTER TRANSPORTER, DOPAMINE), MEMBER 3; SLC6A3

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