PRO-CALCITONIN, SERUM

Method and Reference values Modification

Test code: 3063

Effective update from 19/04/16

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Enzymoimmunoanalysis        Less than 0.5 µg/L Form 0.5 to 2.0 µg/L Systemic Inflammatory Response Syndrome (SIRS), Polytraumatism, Burns. Greater than 2.0 µg/L Severe Bacterial Infeccions, Septicemia.

Chemiluminescence                   Reference limits: Newborns: 0- 6 hours: 2.0 ng/mL  6 to 12 hors: 8.0 ng/mL 12 to 18 hours: 15.0 ng/mL 18-30 hours:  21 .0 ng/mL 30-36 hours: 15.0 ng/mL 36-42 hours: 8.0 ng/mL 42-48 hours : 2.0 ng/mL From 48 hours and adults: up to 0.05 ng/mL Interpretation of results: Diagnosis of sepsis/systemic bacterial infection: · Procalcitonin <0.5 ng/mL: Not likely a systemic infection (sepsis) · Procalcitonin between 0.5 and 2 ng/mL: Is a systemic infection (sepsis) · Procalcitonin between 2 and 10 ng/mL: There is probably a systemic infection (sepsis) · Procalcitonin> 10 ng/mL: Important systemic inflammatory reaction due almost exclusively to severe bacterial sepsis or septic shock. Differential diagnosis of infection of the lower respiratory tract: · Procalcitonin <0.1 ng/mL: Absence of bacterial infection · Procalcitonin between 0.1 and 0.25 ng/mL: Unlikely bacterial infection · Procalcitonin between 0.25 and 0.5 ng/mL: Possible bacterial infection · Procalcitonin> 0.5 ng/mL: Probable presence of bacterial infection           Source: Insert and manufacturer documentation

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