METHOTREXATE, SERUM

Reference values Modification

Test code: 386

Effective update from 03/01/2019

PREVIOUS	NEW
Minimum cytotoxic concentration: Greater than 0.01 µmol/L       Concentration highly toxic:       24 hours: Greater than 5    µmol/L       48 hours: Greater than 0.5  µmol/L       72 hours: Greater than 0.05 µmol/L	Concentration highly toxic:       24 hours: Greater than 10.0 µmol/L       48 hours: Greater than 1.0  µmol/L       72 hours: Greater than 0.2  µmol/L

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TESTOSTERONE FREE, SALIVE

Reference values Modification

Test code: 3976

Effective update from 03/01/2019

PREVIOUS	NEW
Frozen saliva	Refrigerated saliva

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TRAMADOL, SERUM

Reference values Modification

Test code: 3601

Effective update from 03/01/2019

PREVIOUS	NEW
0.20 - 0.80 mg/L       LOD: 0.01 mg/L	0.1 - 0.8 mg/L           LOD: 0,037 mg/L      LOQ: 0,050 mg/L

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M2-PK PIRUVATE-KINASE, Stool

New Test in NOÛS Catalog

Test Code: 7984

Sample:	Stool
Conservation:	Refrigerated
Method:	Enzyme Immunoassay
Set Up Days:	Daily
Delivery term:	23 days

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M2-PK PIRUVATE-KINASE, PLASMA

New Test in NOÛS Catalog

Test Code: 7997

Sample:	Plasma - EDTA (2 ml)
Conservation:	Frozen
Method:	Enzyme Immunoassay
Set Up Days:	Daily
Delivery term:	7 days

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SPERM ANTIBODIES, SEMINAL PLASMA

New Test in NOÛS Catalog

Test Code: 7999

Sample:	Semen
Conservation:	Refrigerated
Method:	Enzyme Immunoassay
Set Up Days:	Daily
Delivery term:	6 days

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Erased tests

Test code: 1115; 3182; 3951; 4336; 5239

Effective update from 31/12/2018

BEFORE	ALTERNATIVE
5239 - Autism, panel (101 genes) NGS, whole blood	7940 - AUTISM - PANEL - NGS
4336 - Nocturnal Frontal Lobe Epilepsy, panel (CHRNA') screening, total blood	1271 - IgE SPECIFIC ANTIBODIES FOR EPITHELIUM DEER (Re216)
1115 - Cerebral Cavernomas (KRIT1) screening, total blood	1116 - Cerebral Cavernomas (KRIT1) sequencing, total blood
3951 - IgG SPECIFIC ANTIBODIES FOR Staphylococcal entero TSST (M226), SERUM	4686 - IgG SPECIFIC ANTIBODIES FOR Staphylococcal entero TSST (M226), SERUM

CORTICOSTERONE - COMPOUND B

Reference values Modification

Test code: 1302

Effective update from 27/12/2018

PREVIOUS	NEW
Age           Boy               Girl     < 1 year: 0.90 - 12.00 µg/L 0.80 - 18.00 µg/L 2 -  5 years: 1.60 - 20.00 µg/L 1.20 - 13.00 µg/L 6 - 12 years: 1.60 - 11.00 µg/L 1.40 - 14.00 µg/L P2 - P3*    : 1.10 -  6.00 µg/L 1.20 - 12.00 µg/L P4 - P5*    : 1.60 -  4.00 µg/L 1.70 -  8.00 µg/L * Puberty stage        Adults: 2.00 - 8.00 µg/L	Age           Boy               Girl     < 1 year: 0.90 - 12.00 µg/L 0.80 - 18.00 µg/L 1 -  5 years: 1.60 - 20.00 µg/L 1.20 - 13.00 µg/L 6 - 12 years: 1.60 - 11.00 µg/L 1.40 - 14.00 µg/L P2 - P3*    : 1.10 -  6.00 µg/L 1.20 - 12.00 µg/L P4 - P5*    : 1.60 -  4.00 µg/L 1.70 -  8.00 µg/L * Puberty stage        Adults: 2.00 - 8.00 µg/L

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COLON NON-POLYPOSIC CANCER - MLH1 - METHYLATION

New Test in NOÛS Catalog

Test Code: 7996

Sample:	Biological Sample
Conservation:	Refrigerated
Method:	Methylation-specific MLPA (MS-MLPA)
Set Up Days:	Daily
Delivery term:	22 days

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PREGNENOLONE, SERUM

Reference values Modification

Test code: 2093

Effective update from 21/12/2018

PREVIOUS	NEW
Male :  0.38 - 3.5 ng/mL       Female: 0.31 - 3.8 ng/mL       * Source: PNT, Insert	Male :  0.10 - 3.40 ng/mL    Female: 0.10 - 3.80 ng/mL    * Source: PNT, Insert

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CARNITINE, (L-CARNITINE), SERUM

Sample Modification

Test code: 2360

Effective update from 21/12/2018

PREVIOUS	NEW
Serum (1mL)	Serum (3mL)

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Cystathionine Beta-Synthase Deficiency (CBS) sequencing, total blood

Delivery Time Modification

Test code: 1286

Effective update from 20/12/2018

PREVIOUS	NEW
Delivery term: 45 days	Delivery term: 32 days

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Multiple Myeloma (MM), panel (del13q, del17p13.1 (p53), amp/del1p36/1q21 (SRD), IgH/CCND1 t(11;14), IgH/FGFR3 t(4;14), IgH/MAF t(14;16)) FISH, total blood/bone marrow

Description Modification

Test code: 3811

Effective update from 19/12/2018

PREVIOUS	NEW
Multiple Myeloma (MM), panel (del13q, del17p13.1 (p53), amp/del1p36/1q21 (SRD), IgH/CCND1 t(11;14), IgH/FGFR3 t(4;14), IgH/MAF t(14;16)) FISH, total blood/bone marrow	MULTIPLE MYELOMA - FISH PANEL

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Enhanced Liver Fibrosis, biomarker (ELF), serum

Delivery Time Modification

Test code: 4929

Effective update from 19/12/2018

PREVIOUS	NEW
Delivery term: 10 days	Delivery term: 9 days

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COMPLEMENT (50%) CH-50, BIOLOGIC SAMPLE

Erased test

Test code: 3517

Effective update from 18/12/2018

Alternative test:

158- COMPLEMENT (50%) CH-50, SERUM 

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Interleukin 6 (IL6), biological fluid

Erased test

Test code: 4825

Effective update from 17/12/2018

Alternative test:

2263- INTERLEUKIN 6 (IL 6) , SERUM

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HEREDITARY MELANOMA - CDK4 - SEQUENCING

New Test in NOÛS Catalog

Test Code: 7987

Sample:	Biological Sample
Conservation:	Refrigerated
Method:	Sequencing Method
Set Up Days:	Daily
Delivery term:	32 days

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BUSCHKE-OLLENDORFF SYNDROME - LEMD3 - SEQUENCING

New Test in NOÛS Catalog

Test Code: 7986

Sample:	Biological Sample
Conservation:	Refrigerated
Method:	Sequencing Method
Set Up Days:	Daily
Delivery term:	32 days

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NONPOLYPOSIS COLON CANCER - MSH6 - MLPA

New Test in NOÛS Catalog

Test Code: 7985

Sample:	Biological Sample
Conservation:	Refrigerated
Method:	Multiplex Ligation-dependent Probe Amplification-MLPA
Set Up Days:	Daily
Delivery term:	22 days

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BIOTINIDASE ACTIVITY, SERUM

Sample and Delivery Time Modification

Test code: 2709

Effective update from 12/12/2018

PREVIOUS	NEW
Sample: serum             Delivery term: 15 days	Sample: plasma               Delivery term: 13 days

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MULTIPLE EPIPHYSEAL DYSPLASIA - PANEL - NGS

New Test in NOÛS Catalog

Test Code: 7983

Sample:	Biological Sample
Conservation:	Refrigerated
Method:	Next Generation Sequencing (NGS)
Set Up Days:	Daily
Delivery term:	57 days

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IgE SPECIFIC ANTIBODIES FOR EPITHELIUM DEER (Re216 )

Erased test

Test code: 3182

Effective update from 11/12/2018

Discontinued test, for shortages and suspension of supply of the reagent by the manufacturer.

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HALOPERIDOL, SERUM

Reference values Modification

Test code: 3219

Effective update from 14/12/2018

PREVIOUS	NEW
2.0 - 25.0 µg/L	1.0 - 10.0 µg/L

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SYNOVIAL FLUID STUDY

Reference values Modification

Test code: 2458

Effective update from 11/12/2018

PREVIOUS	NEW
Not detected.	Crystals : Not detected.       Cells : <200 leukocytes="" mm3="" polymorphonuclear="" span="">       Glucose : Not available       Total prot. : Not available

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