CYCLOSPORIN, WHOLE BLOOD

Method, Reference values and Delivery Time Modification

Test code: 945

Effective update from 01/03/2019

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Method: Enzyme multiplied immunoassay technique           RENAL TRANSPLANT: post-trasplant Time     Therapeutic Phase       1 month 200 - 250 ng/mL       2 - 3 months 175 - 200 ng/mL       3 - 6 months 150 _ 175 ng/mL       6 -12 months 125 - 150 ng/mL       > 12 months 100 - 200 ng/mL          LIVER TRANSPLANT : 5 - 6 days 250 - 350 ng/mL       8 - 14 days 300 - 350 ng/mL       More than 14 days 200 - 250 ng/mL       More than 12 months 100 - 200 ng/mL    HEART TRANSPLANT : 1 - 5 days 250 - 350 ng/mL       > 14 days 300 - 350 ng/mL       * Fuente: PNT, Insert             Delivery term: 2 days

Method: Liquid Chromatography/Tandem Mass Spectrometry                   Post-transplant Therapy Renal transplant          150-225 ng/mL  Liver transplant   225-300 ng/mL Heart transplant   250-350 ng/mL         Maintenance Therapy Renal transplant         100-150 ng/mL  Liver transplant  100-150 ng/mL Heart transplant  150-250 ng/mL                            Delivery term: 4 days

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