CLOMIPRAMINE / DISMETHYLCLOMIPRAMINE , SERUM

Reference values Modification

Test code: 799

Mnemonic code: CLDE

Effective update from 26/02/2024

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CLOMIPRAMINE: 20 - 250 µg/L       DISMETHILCLOMIPRAMINE: 20 - 250 µg/L             * Fuente: PNT, Insert             Version of Test: 9

Therapeutic level: Clomipramine*: 90-250 µg/L Desmethilclomipramine**: 150 - 300 µg/L       Toxicity (Clomipramine)*: Greater than 400 µg/L  LoQ (Clomipramine): 10 µg/L LoQ (Desmethilclomipramine): 12 µg/L   *Source: M. Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020                **Source: PNT, insert                              Version of Test: 10

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