PRO-INSULIN INTACT, PLASMA

Reminder Sample Modification - Interpretative Note Reference Values 

Test code: 2491

Mnemonic code: PROIN

Effective update from 07/02/2024

Dear colleagues and collaborators,

We remind you that, as we communicated last 19th of January of 2024, the sample indicated for Proinsulin analysis is Frozen Plasma-EDTA.

The serum sample is not the sample of choice for this determination anymore, for the reasons stated in this mail, so it should no longer be delivered. We ask you to take note of the changes and pass them on to anyone who may be interested.

Since it has been detected in the laboratory that serum samples are still being received for proinsulin analysis, we will temporarily include in the reports a note for the correct interpretation of the results obtained when serum samples are analyzed:

Serum values are 15-20% lower compared to plasma samples, due to the presence of proteases in serum.

The serum result must be interpreted according to clinical criteria.

Source: Manufacturer's insert.

This note will appear in the reports until 01/03/2024, considering that, from this date, only EDTA Plasma samples will be received for this determination and the note will no longer be necessary.

The current version of the test is 13, adding this note will cause to change it to version 14.

We thank you in advance for your collaboration.

 

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Less than 4.21 pmol/L       * Source: PNT, Insert                               Version of Test: 13	Less than 4.21 pmol/L        Serum values are 15-20% lower compared to plasma samples, due to the presence of proteases in serum.    The serum result must be interpreted according to clinical criteria.    *Source: Manufacturer's insert.    Version of Test: 14

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