FLUOXETINE AND DESMETHLYFLUOXETINE, SERUM

Units and Reference values Modification

Test code: 3177

Mnemonic code: FLUO

Effective update from 18/03/2023

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Units: ng/mL       Fluoxetine + Norfluoxetine : 120 - 500 ng/mL       LoQ: 25 ng/mL             NOTE:Norfluoxetine is an active metabolite, its level is important when fluoxetine is very low or undetectable. When fluoxetine is in the therapeutic zone, the associated level of norfluoxetine confirm a good treatment response.                               Version of Test: 22

Units: µg/L    Therapeutic Range: Fluoxetine + Norfluoxetine : 120 - 500 µg/L    Toxicity: Greater than 1000 µg/L    LoQ: 15 µg/L    NOTE:Norfluoxetine is an active metabolite, its level is important when fluoxetine is very low or undetectable. When fluoxetine is in the therapeutic zone, the associated level of norfluoxetine confirm a good treatment response.                            *Source: M. Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020.               Version of Test: 23

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