Friday, March 7, 2025

CALCIUM CHANNELS (TYPE P) ANTIBODIES, SERUM

Reference values Modification

Test code: 7001
Mnemonic code: CANCA

Effective update from 17/03/2025




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NEW
        
Negative: Less than or equal to 30 pmol/L
Positive: Greater than 30 pmol/L
     
Antibodies to calcium channels of the P/Q type are detected in more than 90% of cases of Lambert-Eato syndrome.
      
     
Version of Test: 11
     

        
Negative: Less than or equal to 30 pmol/L
Positive: Greater than 30 pmol/L         

                 
The antibodies against calcium channels (VGCC) can be classified based on their electrophysiological characteristics into at least 4 subtypes (L, N, P, and T). The detection of antibodies against P-type calcium channels is crucial for the diagnosis of Lambert-Eaton Syndrome, being present in approximately 85-90% of patients     
Version of Test: 12
     

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