AMYLOID BETA PROTEIN/TAU, CSF

Result Format and Reference values Modification

Test code: 1445

Mnemonic code: BTLB

Effective update from 14/04/2025

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Result Format:   R1 Beta Amyloid 1-42 protein:   R2 TAU proteine:   R3 Phosphorylated TAU protein:   R4 Ratio Beta amyloid (1-42/1-40):   Reference Values:   BETA AMYLOID 1-42 PROTEIN : Greater than 600 pg/mL   TAU PROTEINE : Less than 385 pg/mL   PHOSPHORYLATED TAU PROTEIN: Less than 65 pg/mL   RATIO BETA AMYLOID (1-42/1-40): Greater than 0.07         Note: In Alzheimer's dementia and prodromal Alzheimer's disease, a decrease in Amyloid beta 42 protein, a reduction in the Ab42/Ab40 ratio, and an increase in both total Tau protein and phosphorylated Tau protein are characteristic.                   Version of Test: 31

Result Format:  R1 Beta Amyloid 1-42 protein:  R2 TAU proteine:  R3 Phosphorylated TAU protein:  R4 Beta Amyloid 1-40:  R5 Ratio Beta Amyloid (1-42/1-40):  Reference Values:  BETA AMYLOID 1-42 PROTEIN : Greater than 599 pg/mL (*)  TAU PROTEINE : Less than 404 pg/mL (*)  PHOSPHORYLATED TAU PROTEIN: Less than 56.5 pg/mL (*)  BETA AMYLOID 1-40 PROTEIN: 7755 - 16715 pg/mL (**)  RATIO BETA AMYLOID (1-42/1-40): Greater than 0.069 (*)   Note: In Alzheimer's dementia and prodromal Alzheimer's disease, a decrease in Amyloid beta 42 protein, a reduction in the Ab42/Ab40 ratio, and an increase in both total Tau protein and phosphorylated Tau protein are characteristic.  (*)Bellomo G, Cataldi S, Paciotti S, et al. Measurement of CSF core Alzheimer disease biomarkers for routine clinical diagnosis: do fresh vs frozen simples differ?. Alzheimer’s Research & Therapy. 2020. 12:121    (**) Insert                                                                Version of Test: 32

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