MOLECULAR STUDY GEN BRAF (V600E), TISSUE

New Test in CIC Catalog

Test Code: 3788

Sample:	Tumoral tissue
Conservation:	Room temperature
Method:	Sequencing Method
Set Up Days:	Daily
TAT (Days):	20 days
Information:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung.
Links:
OMIM Entry - -164757 - V-RAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B1; BRAF
BRAF Gene - GeneCards - BRAF Protein - BRAF Antibody

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