HLA-B51/B52 (HLA-B5) genotype, whole blood

Information about this test

Test code: 5121

Effective update from 30/07/15

Erase test was notified  incorrectly. By this we inform you that remains valid.

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HLA-B27, WHOLE BLOOD

Information about this test

Test code: 129

Effective update from 30/07/15

Erase test was notified  incorrectly. By this we inform you that remains valid.

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HLA-B5701 genotype (susceptibility to Abacavir), total blood

Information about this test

Test code: 3467

Effective update from 30/07/15

Erase test was notified  incorrectly. By this we inform you that remains valid.

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HLA DQ, WHOLE BLOOD

Erase Test

Test code: 3090, 2878, 2107 and 1028

Effective update from 31/07/15

All these tests will be replaced by: MOLECULAR STUDY GENOTYPE HLA-DQB1 (high resolution), whole blood (5263).

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MOLECULAR STUDY GENOTYPE HLA-DQB1 (high resolution), whole blood

New Test in NOÛS Catalog

Test Code: 5263

Sample:	Whole blood EDTA (10 ml)
Conservation:	Refrigerated
Method:	PCR-SSO
Set Up Days:	Daily
Delivery term:	15 days
Information:
The major histocompatibility complex (MHC), is a family of genes constitute the so-called HLA (for human leukocyte antigen) system; they are essential in the body's immune defense against pathogens, and on the other hand, constitute the main barrier to organ transplantation and stem cell. Its discovery has enabled medicine to make a qualitative leap on the chances for success of a transplant, opening a promising path, whose major trouble was the organ rejection. It could also be discovered connection between certain HLA profiles and a higher frequency of autoimmune diseases such as systemic lupus erythematosus, myasthenia gravis, Sjögren's syndrome, or other like ankylosing spondylitis and celiac disease, etc. Until recently, serological techniques have used and they have based on cytotoxicity (cell lysis mediated by specific antibodies in the presence of complement); the technique is manual, cumbersome and its interpretation is subjective. The development in molecular biology techniques has enabled the use of more precise techniques, with higher reducibility and resolution and higher automation. PCR-SSOP (polymerase chain reaction-sequence specific oligonucleotide probe) is the most commonly used method due to its and in cases where higher resolution is required to allelic level, the PCR-SSP technique is used (polymerase chain reaction-sequence specific primers). For this reason, Labco NOÛS has decided to support the integration of these new techniques instead of the traditional methods.

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CLOZAPINE, SERUM

Reference values Time Modification

Test code: 2890

Effective update from 03/08/15

PREVIOUS	NEW
300 - 800 µg/L	50 - 700 ng/mL

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HLA-DR (high resolution) genotype, total blood

Erase test

Test code: 3936

Effective update from 30/07/15

Tthese tests will be replaced by: MOLECULAR STUDY HLA-DRB1 (high resolution), whole blood (4476)

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ANTIGEN HLA-DR, total blood

Erase Test

Test code: 1568, 678, 2749, 680, 679, 4168, 677, 859, 888, 901 and 2294

Effective update from 30/07/15

All these tests will be replaced by:MOLECULAR STUDY HLA-DRB1 (low resolution) , total blood (2870)

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HLA-B27, WHOLE BLOOD

Erase Test

Test code: 129 and 780

Effective update from 30/07/15

All these tests will be replaced by: HLA-B27 genotype, total blood (2909)

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ANTIGENS MHC-B, WHOLE BLOOD

Erase test

Test codes: 3467, 5121, 400, 781, 789, 788, 2125, 2223, 896, 995, 2020, 699, 779, 869, 897, 955, 963, 2044, 2215, 2224, 2379, 2972, 400.

Effective update from 29/07/15

All these tests will be replaced by: MOLECULAR STUDY GENOTYPE MHC-B (LOW RESOLUTION), WHOLE BLOOD (3867)

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ANTIGENS MHC-C, WHOLE BLOOD

Erase Test

Test code: 956, 994, 2869, 3931

Effective update from 29/07/15

All these tests will be replaced by:MOLECULAR STUDY GENOTYPE MHC-C (LOW RESOLUTION), WHOLE BLOOD (4475)

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ANTIGENS MHC-A, WHOLE BLOOD

Erase test

Test code: 895, 778, 904, 919, 996, 2386

Effective update from 28/07/15

All these tests will be replaced by:MOLECULAR STUDY GENOTYPE MHC-A (LOW RESOLUTION), WHOLE BLOOD (3930)

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PRO-INSULIN INTACT, SERUM/PLASMA

Reference values Modification

Test code: 2491

Effective update from 29/07/15

PREVIOUS	NEW
Serum: 0.5 - 3.5 pmol/L        Plasma: 0.7 - 8.0 pmol/L              * Source: PNT, Insert	Adults:            Serum: 0.7 - 4.3 pmol/L     Plasma: 0.7 - 8.3 pmol/L Children (serum): 0.5 - 3.5 pmol/L        * Source: PNT, Insert

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IgE specific antibodies for nCor 9 Hazel nut F440 (recombinant)

New Test in NOÛS Catalog

Test Code: 5261

Sample:	Serum (1 ml)
Conservation:	Refrigerated
Method:	ImmunoCAP
Set Up Days:	Daily
Delivery term:	4 days

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11-Desoxycortisol, serum

Reference values Modification

Test code: 334

Effective update from 22/07/15 (CORRECTION INSERT BY THE MANUFACTURER)

PREVIOUS	NEW
Without stimulus : Less than 7.2 ng/mL Post metopirone : 72-255 ng/mL        * Fuente: PNT, Insert	Without stimulus : Less than 2.55 ng/mL Post metopirone : 72-255 ng/mL        * Fuente: PNT, Insert

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VITAMIN D (25-HYDROXY-CHOLECALCIFEROL), SERUM

Reference values 

Test code: 361

Effective update from 23/07/2015

PREVIOUS	NEW
Deficiency: 0-10 ng/mL       Insufficiency: 10- 30 ng/mL       Sufficiency: 30-150 ng/ mL       Toxicity: > 150 ng/mL       Note:       Season, race and dietary intake affect the normal levels of 25-hydroxy-Vitamin D.       * Fuente: PNT, Insert	Deficiency: <10 ng/mL       Insufficiency: 10- 29 ng/mL       Sufficiency: 30-100 ng/ mL       Toxicity: > 100 ng/mL       Note:       Season, race and dietary intake affect the normal levels of 25-hydroxy-Vitamin D.       * Source: PNT, Insert

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PHOSPHOLIPASE (k203)

Test Code: 2712

Discontinued for technical reason.

PRO-CALCITONIN, PLASMA

Sample Modification

Test code: 3063

Effective update from 10/07/15

PREVIOUS	NEW
Frozen heparin plasma (1 mL)	Frozen serum (1 mL)           Alternative: Heparin-Plasma, EDTA-Plasma, frozen.

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Breath test - bacterial overgrowth (Lactitol)

Delivery Time Modification

Test code: 4781

Effective update from 10/07/15

PREVIOUS	NEW
Delivery term: 4 days	Delivery term: 13 days

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BORRELIA BURGDORFERI IgM ANTIBODIES, SERUM

Method and Reference values Modifications

Test code: 1014

Effective update from 13/07/15

PREVIOUS	NEW
ENZYME IMMUNOASSAY               NEGATIVE : Index less than 1.00             * Positive IgM antibody can be compatible       with recent infection.              * Fuente: PNT, Insert	CHEMILUMINESCENCE                    NEGATIVE   : Less to 0.90 GREY ZONE: Between 0.90 - 1.10 POSITIVE    : Grater or equal tan 1.10 * Positive IgM antibody can be compatible with recent infection.          * Source: PNT, Insert

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BORRELIA BURGDORFERI IgG ANTIBODIES, SERUM

Method and Reference values Modifications

Test code: 962

Effective update from 13/07/15

PREVIOUS	NEW
ENZYME IMMUNOASSAY        NEGATIVE: Index < 0.90 Grey Zone : Index 0.90 - 1.10 POSITIVE : Index > 1.10       * To descard Active or Acute Infection, IgM antibody or IgG seroconversion (Increased levels 2 or more times indicates active infection).           * Fuente: PNT, Insert	CHEMILUMINESCENCE           NEGATIVE   : Less to 10 AU/mL GREY ZONE : Between 10 - 15 UA/mL POSITIVE     : Grater or equal tan 15 UA/mL * To descard recent infection should be evaluated IgM or IgG seroconversion in 3-4 weeks.                    * Source: PNT, Insert

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Risk index - first trimester screenning (PAPP-A, Free Beta-HCG) , serum

Reference values Modification

Test code: 5181

Effective update from 09/07/15

PREVIOUS	NEW
We recommend further study, if the patient's Down syndrome risk is equal to or greater than 1 in 270.             We recommend further study, if the patient's Edwards' syndrome risk is equal to or greater than 1 in 250	We recommend further study, if the patient's Down syndrome risk is equal to or greater than 1 in 250.             We recommend further study, if the patient's Edwards' syndrome risk is equal to or greater than 1 in 250

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CYTOMEGALOVIRUS IgG ANTIBODIES AVIDITY TEST

Method Modification

Test code: 3046

Effective update from 08/07/15

PREVIOUS	NEW
Fluoroimmunoassay	Enzyme Immmunoassay

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Human Immunodeficiency Virus type 1 (HIV-1) protease, reverse transcriptase genotype (PR, RT), plasma

Relative information 

Test code: 2765

It is reported that for determination 2765 - Human Immunodeficiency Virus Type 1 (HIV-1) protease, reverse transcriptase genotype (PR, RT), plasma,  the sequencing service will not be available from 1 to 16 August. Therefore, samples arriving from July 13 will be stored and processed as of August 17.