Test code: 261
Effective update from 02/05/2016
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1.2 - 2.6 mg/dL * Fuente: PNT, Insert Delivery term: 1 | 13-26 mg/L |
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1.2 - 2.6 mg/dL * Fuente: PNT, Insert Delivery term: 1 | 13-26 mg/L |
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Delivery term: 15 days | Delivery term: 4 days |
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Delivery term: 10 days
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Delivery term: 3 days
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Test Code: 5420
Sample: Serum (1 ml) Conservation: Refrigerated Method: ImmunoCAP Set Up Days: Daily Delivery term: 1 daysFind the record of the test by clicking here
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Less than 100 U/mL * Source: PNT, Insert | Until 100 U/mL * Source: PNT, Insert |
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Assesment under clinical criteria
Reference values for serum samples:
Negative: Less than 0.8
Grey zone: 0.8 - 1.2
Positive: Greater than 1.2
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Assesment under clinical criteria
Reference values for serum samples:
Negative: Less or equal than 15
Grey zone: 16 - 21
Positive: Equal or greater than 22
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NEGATIVE: Titer 1/10 * Source: PNT, Insert | NEGATIVE: Titer less than 1/10 * Source: PNT, Insert |
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NEGATIVE: Titer 1/20 * Source: PNT, Insert | NEGATIVE: Titer less than 1/20 * Source: PNT, Insert |
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NEGATIVE: Titer 1/10 | Negative: Less than 1/8 |
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NEGATIVE: Titer 1/40 | Negative: Less than 1/40 |
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NEGATIVE: Titer 1/10
* Source: PNT, Insert
NEGATIVE: Titer less than 1/32
* Source: PNT, Insert
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NEGATIVE: Titer 1/160
* Source: PNT, Insert
NEGATIVE: Titer less than 1/32
* Source: PNT, Insert
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Cosackie A9 IgG: NEGATIVE: Titer 1/40
Coxsakie A9 IgM: NEGATIVE: Titer 1/10 |
Cosackie A9 IgG: NEGATIVE: Titer less than 1/40
Coxsakie A9 IgM: NEGATIVE: Titer less than 1/10 |
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Refrigerated biological sample
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Frozen biological sample
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Test Code: 5414
Sample: Serum (2 ml) Conservation: Refrigerated Method: Liquid Chromatography/Tandem Mass Spectrometry Set Up Days: Daily Delivery term: 16 daysFind the record of the test by clicking here
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Clobazam,serum
CLOBAZAM Therapeutic level: 200 - 500 ng/mL
Note: The presence of Norclobazam be assessed only in the case of therapy without Clonazepam.
Clobazam and Clonazepam therapy can interfere with both determinations.
NORCLOBAZAM Orientative Therapeutic level: 1000 - 3000 ng/mL
* Krapf,FE, Bieger WP,Tiller FW. LaborDatenBuch (1995) Urban & Schwarzenberg, München.
* Source: PNT, Insert
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Clobazam, norclobazam and ratio, serum
. Therapeutic Area:
Clobazam : 30 -
300 µg/L
Norclobazam: 300 - 3000 µg/L
Norclobazam/Clobazam Ratio: Less than 10
. Toxic Concentration:
Clobazam : Higher
to 3000 µg/L
Norclobazam : Higher to 12000 µg/L
. Comment: The Norclobazam/Clobazam ratio may be useful for
information on the drug metabolizing capacity and improve dose adjustment. Very
high ratios (> 25) indicate that the patient is a poor metabolizer of
CYP2C19 (if not taking drugs that induce CYP3A or CYP2C19 inhibitors).
Note: The presence of Norclobazam must be evaluated only if
no Clonazepam therapy because it interferes with the analytical determination.
*Ther Drug Monit. 2013 Feb;35(1):30-47. doi:
10.1097/FTD.0b013e31827ada88.
Clobazam therapeutic drug monitoring: a comprehensive review
of the literature with proposals to improve future studies.
De Leon J, Spina E, Diaz FJ.
* Source: Literature values
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Delivery term: 5 days | Delivery term: 10 days We communicate the modification of delivery due to lack of reagent on the market. When delivery is normalized, the deadline above (5 days) will be restored. |
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