Thursday, August 11, 2022

NEISSERIA GONHORREAE TOTAL ANTIBODIES, SERUM

Erased test

Test code: 8758
Nemonic code: ANEGM

Effective update from 11/08/2022

Dear collegues and colaborators,

 We inform you that after the recent review of the available literature on the parameter Neisseria Gonorrheae IgG/IgM Total Antibodies, the parameter has been discontinued because serology and enzyme-linked immunosorbent assays are useless for the diagnosis of gonococcal infection due to their low sensitivity and specificity.

 Currently the methods recommended by national and international guidelines for the diagnosis of gonorrhea include culture (samples of urethral, endocervical, vaginal, pharyngeal or rectal exudates) and molecular biology techniques (these techniques are currently the first choice).

 This is reflected in the most recent CDC guide (Sexually Transmitted Infections Treatment Guidelines) and also in the guide of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC).

  For these reasons, we are proceeding to permanently discontinue the 8758 Neisseria Gonorrheae Total Antibodies test, offering molecular biology techniques as the first option for diagnosis, and culture as the last option.

 For more information, if you wish, we indicate the associated bibliography:

1. Kimberly A Workowski, Laura H Bachmann, Philip A Chan, Christine M Johnston, Christina A Muzny, Ina Park, Hilary Reno, Jonathan M Zenilman, Gail A BolanSexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1.  

 https://www.cdc.gov/std/treatment-guidelines/STI-Guidelines-2021.pdf

 2. Galán Montemayor JC, Lepe Jiménez JA, Otero Guerra L, Serra Pladevall J, Vázquez Valdés F. Diagnóstico microbiológico de las infecciones de transmisión sexual y otras infecciones genitales. 2018. 24a. Vázquez Valdés F (coordinador). Procedimientos en Microbiología Clínica. Cercenado Mansilla E, Cantón Moreno R (editores). Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC). 2018

 https://seimc.org/contenidos/documentoscientificos/procedimientosmicrobiologia/seimc-procedimientomicrobiologia24a.pdf

  For any clarification in this regard, do not hesitate to contact us.


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