Friday, March 31, 2023

SULFONYLUREA, SERUM AND URINE

Delivery Time Modification

Test code: 2860 and 2861
Nemonic code: SULF and SULFO

Effective update from 11/04/2023




PREVIOUS

NEW
        
     Delivery term: 21 days
     
     

        
     Delivery term: 18 days
     
   
     

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Thursday, March 30, 2023

ISAVUCONAZOL, PLASMA

New Test in NOÛS Catalog

Test Code: 9818

Sample:
Plasma (EDTA) Frozen (2 ml)
Conservation:
Frozen
Method:
Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Set Up Days:
Daily
Delivery term:
7 days

    Find the record of the test by clicking here

RITUXIMAB, SERUM

New Test in NOÛS Catalog

Test Code: 9817

Sample:
Serum (1 ml)
Conservation:
Frozen
Method:
Enzyme Immunoassay
Set Up Days:
Daily
Delivery term:
14 days

    Find the record of the test by clicking here

Wednesday, March 29, 2023

HEPATITIS B SURFACE ANTIGEN (HBs-Ag)-CONFIRMATION, SERUM

Reference values and Additional information Modification

Test code: 2195
Nemonic code: AGBSC

Effective update from 11/04/2023




PREVIOUS

NEW
        
      Method: Chemiluminescence


      Not detected.
     
     
      



       Version of Test: 6
     


        
   Method: Neutralization test      
         
   Interpretation criteria:
      % Neutralization <50%. Surface antigen positivity is not confirmed.
      % Neutralization ≥50%. Surface antigen positivity is confirmed
      


   Version of Test: 7
     


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Measles IgG/IgM antibodies, serum

Reference values and Delivery Time Modification

Test code: 5212

Effective update from dd/mm/aa




PREVIOUS

NEW
 Method: Enzyme Immunoassay


 References values:

 -Measles IgG antibodies:

  Negative: Index Less than 1.00
  Positive low: Index 1.00 - 2.49
  Positivo medium: Index 2.50 - 4.29
  Positive high: Index greater than 4.30

  * To descard active infection is recommended to evaluate IgM MUMPS antibody or to do seroconversion for IgG MUMPS antibody after 2 weeks of first sample. Increasing of index 2 or more times indicates active infection.


 -Measles IgM antibodies:

  Negative: Index less than 1.0

  * Positive IGM - SARAMPION antibody can be compatible with recent infection.

  * Source: PNT, Insert




  Delivery term: 5 days


  Version of Test: 22
     


 Method:  Chemiluminescence


 Reference values:

 -Measles IgG antibodies:

  Negative: Index Less than 0.9
  Indeterminate: Index 0.9 - 1.1
  Positive: Index greater than 1.1


  * To descard active infection is recommended to evaluate IgM MUMPS antibody or to do seroconversion for IgG MUMPS antibody after 3 - 4 weeks of first sample. Increasing of index 2 or more times indicates active infection.


 -Measles IgM antibodies:

  Negative: Index Less than 0.9
  Indeterminate: Index 0.9 - 1.1
  Positive: Index greater than 1.1

  * Positive IGM - SARAMPION antibody can be
        compatible with recent infection.

  * Source: PNT, Insert



  Delivery term: 2 days


  Version of Test: 23     
         
         
       
     


   Find the record of the test by clicking here

TOSCANA VIRUS RNA, CSF

New Test in NOÛS Catalog

Test Code: 9811

Sample:
Cerebrospinal Fluid - CSF(1ml)
Conservation:
Frozen
Method:
Real-Time PCR
Set Up Days:
Daily
Delivery term:
12 days
Information:
Clinical information of the patient is necessary

    Find the record of the test by clicking here

NICKEL, URINE (µg/g creatinine)

Reference values Modification

Test code: 550
Nemonic code: NIQO

Effective update from 11/04/2023




PREVIOUS

NEW
        
      No occupational exposure:
      Less than 2 µg/g creatinine.
     
      Occupational exposure:
      BEI: Less than 30 µg/g creatinine.
      * Fuente: PNT, Insert
     
      
      Version of Test: 11
     


BEI (ACGIH 2022): after exposure to elemental Nickel and insoluble compounds: 5 µg/L

BEI (ACGIH 2022): after exposure to insoluble compounds: 30 µg/L

   *B.E.I. - Biological Exposure Index.        

   Version of Test: 12
     



   Find the record of the test by clicking here

NEUROPHATY (EXPANDED) · PANEL · NGS

New Test in NOÛS Catalog

Test Code: 9816

Sample:
Biological Sample
Conservation:
Refrigerated
Method:
Next Generation Sequencing (NGS)
Set Up Days:
Daily
Delivery term:
42 days

    Find the record of the test by clicking here

Monday, March 27, 2023

ATYPICAL HEMOLYTIC-UREMIC SYNDROME · PANEL · MLPA

New Test in NOÛS Catalog

Test Code: 9815

Sample:
Biological Sample
Conservation:
Refrigerated
Method:
Multiplex Ligation-dependent Probe Amplification-MLPA
Set Up Days:
Daily
Delivery term:
22 days

    Find the record of the test by clicking here

Friday, March 24, 2023

GOLIMUMAB / ANTI-GOLIMUMAB ANTIBODIES, SERUM

New Test in NOÛS Catalog

Test Code: 9812

Sample:
Serum (2 ml)
Conservation:
Refrigerated
Method:
Enzyme Immunoassay
Set Up Days:
Daily
Delivery term:
7 days

    Find the record of the test by clicking here

VEDOLIZUMAB / ANTI-VEDOLIZUMAB ANTIBODIES, SERUM

New Test in NOÛS Catalog

Test Code: 9813

Sample:
Serum (2 ml)
Conservation:
Refrigerated
Method:
Enzyme Immunoassay
Set Up Days:
Daily
Delivery term:
7 days

    Find the record of the test by clicking here

USTEKINUMAB / ANTI-USTEKINUMAB ANTIBODIES, SERUM

New Test in NOÛS Catalog

Test Code: 9814

Sample:
Serum (2 ml)
Conservation:
Refrigerated
Method:
Chemiluminescence
Set Up Days:
Daily
Delivery term:
7 days

    Find the record of the test by clicking here

Thursday, March 23, 2023

BROMIDE, URINE

Method Modification

Test code: 3562

Effective update from 03/04/2023



PREVIOUS

NEW
        
      Ion Selective Electrode
     
     
      Version of Test: 2
     

        
  Inductively Coupled Plasma/ Mass Spectrometry (ICP-MS)       
         
      Version of Test: 3
     

   Find the record of the test by clicking here

Beta 2 Defensin, Stool

Delivery Time Modification

Test code: 7632
Nemonic code:  B2DEFH 

Effective update from 27/03/2023




PREVIOUS

NEW
      
      Delivery term: 9 days
     
        
      Delivery term: 13 days
     
     

   Find the record of the test by clicking here

Tuesday, March 21, 2023

METHANOL, SERUM

New Test in NOÛS Catalog

Test Code: 9810

Sample:
Serum (5 ml)
Conservation:
Refrigerated
Method:
Gas Chromatography
Set Up Days:
Daily
Delivery term:
2 days

    Find the record of the test by clicking here

Friday, March 17, 2023

Plasmodium DNA, total blood

Delivery Time Modification, Additional information (*)

Test code: 2964
Nemonic code: DBPS

Effective update from 03/27/2023




PREVIOUS

NEW
        
          
     
      Delivery term: 8 days      

        
         
         
     Delivery term: 4 days

     

 (*)  Note: For positive results, the coded species will be reported.


 Find the record of the test by clicking here

Thursday, March 16, 2023

Karyotype, total blood, amniotic fluid, haematological, tissue, total cord blood, fibroblasts, culture, chorionic villus (culture)

Reference values Modification

Test code: 684, 907, 1106, 2260, 2533, 5446, 3474
Nemonic code: Does not apply

Effective update from 03/27/2023

Test Code: 684

 

Karyotype, total blood

 

Previous References Values

New References Values

Technique: Cell culture for 48-72 hours stimulated with PHA (phytohemagglutinin). G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 15.
Limitations: This result does not include chromosomal findings interpreted as normal variants (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of analysis. studies, such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities and discrepancies between tissues.

4. Methodology
             Cell culture (48h and 72h) stimulated with PHA (phytohemaglutinin). Identification by G bands (ISCN 2020). Resolution: 400-550 bands. Minimum number of metaphases analyzed: 15.

5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies and discrepancies between tissues.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the  clinical context of the patient and according to medical criteria.

Test Code: 907

 

Karyotype, amniotic fluid

 

Previous References Values

New References Values

Technique: Cell culture. Analysis of two independent cultures. G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 20.
Limitations: This result does not include the findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of study. such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities, discrepancies between tissues and contamination with maternal cells.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

4. Methodology
             Cell culture. Identification by G bands (ISCN 2020) from two independent cultures. Resolution: 400-550 bands. Minimum number of metaphases analyzed: 20.

5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies, discrepancies between tissues and maternal contamination.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the clinical context of the patient and according to medical criteria.

Test Code: 1016

 

Karyotype haematological

 

Previous References Values

New References Values

Technique: Cell culture (24 hours without stimulation and/or 72 hours stimulated with TPA (tetradecanoylphorbol acetate) or PHA (phytohemagglutinin), depending on diagnostic orientation). G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 20.
Limitations: This result does not include the findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of study. , mainly the absence of growth of pathological cells, the possible non-detection of some mosaics and small structural alterations.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

             4. Methodology                                                                                             Cell culture, with or without stimulation with TPA (tetradecanoylphorbol acetate) or PHA (phytohemagglutinin), depending on diagnostic orientation*. Identification by G bands (ISCN 2020) in two independent cultures. Resolution: 300-400 bands. Minimum number of metaphases analyzed: 20

             *1) Myeloproliferative neoplasia, Myelodysplastic syndrome, Acute leukemia, not indicated: direct cultures and 24 hours without mitogen. 2) Multiple myeloma: direct cultures and 72 hours without mitogen. 3)Chronic Lymphoproliferative Syndrome of B cells, Chronic Lymphoid Leukemia: direct cultures and 72 hours stimulated with TPA. 4) Chronic Lymphoproliferative Syndrome of T cells: direct cultures and 72 hours stipulated with PHA.

5. Limitations and recommendations
             - This result is issued following the criteria of the European Cytogeneticists Association (ECA),http//www.e-c-a.eu/EN/GUIDELINES.html).
             - This study does not include chromosomal findings interpreted as normal variants and is subject to the limitations of this type of study, mainly the absence of growth of pathological cells, the possible non-detection of some mosaics and small structural alterations.
             - The guidelines indicate that the conventional karyotype is not the most recommended analysis in cases of MM, although it can be performed to complete the study if there is a sufficient sample (Multiple Myeloma Guideline of the Spanish Group, 2021).
             - This report must be accompanied by the corresponding karyotype image(s) and must be interpreted within the clinical context of the patient and according to medical criteria.

Test Code: 2260

 

Karyotype, tissue

 

Previous References Values

New References Values

Technique: Cell culture. G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 15.
Limitations: This result does not include the findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of study. such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities, discrepancies between tissues and contamination with maternal cells.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

4. Methodology
             Cell culture. Identification by G bands (ISCN 2020). Resolution: 400-550 bands. Minimum number of metaphases analyzed: 15.

5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European
             Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies, discrepancies between tissues and maternal contamination.
             - This report must be accompanied by the corresponding karyotype image(s) and must be interpreted within the clinical context of the patient and according to medical criteria.

Test Code: 2533

 

Karyotype, total cord blood

 

Previous References Values

New References Values

Technique: Cell culture for 48-72 hours stimulated with PHA (phytohemagglutinin). G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 15.
Limitations: This result does not include chromosomal findings interpreted as normal variants (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of analysis. studies, such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities and discrepancies between tissues.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

4. Methodology
             Cell culture (48h and 72h) stimulated with PHA (phytohemaglutinin). Identification by G bands (ISCN 2020). Resolution: 400-550 bands. Minimum number of metaphases analyzed: 15.

             5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies, discrepancies between tissues and maternal contamination.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the clinical context of the patient and according to medical criteria.

Test Code: 5446

 

Karyotype, fibroblasts

 

Previous References Values

New References Values

Technique: Cell culture. G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 15.
Limitations: This result does not include the findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of study. such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities, discrepancies between tissues and contamination with maternal cells.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

4. Methodology
             Cell culture. Identification by G bands (ISCN 2020) from two independent cultures. Resolution: 400-550 bands. Minimum number of metaphases analyzed: 20.

5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies, discrepancies between tissues and maternal contamination.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the clinical context of the patient and according to medical criteria.

Test Code: 9605

 

Karyotype, culture

 

Previous References Values

New References Values

Technique: Cell culture for 48-72 hours stimulated with PHA (phytohemagglutinin). G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 15.
Limitations: This result does not include chromosomal findings interpreted as normal variants (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of analysis. studies, such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities and discrepancies between tissues.

4. Methodology
             Cell culture (48h and 72h) stimulated with PHA (phytohemaglutinin). Identification by G bands (ISCN 2020). Resolution: 400-550 bands. Minimum number of metaphases analyzed: 15.

5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies and discrepancies between tissues.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the  clinical context of the patient and according to medical criteria.

Test Code: 3474

 

Karyotype, chorionic villus (culture)

 

Previous References Values

New References Values

Technique: Cell culture. Analysis of two independent cultures. G-Banded Chromosomal Analysis (2020). Resolution level: 400-550 bands. Minimum number of metaphases studied: 20.
Limitations: This result does not include the findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of study. such as, among others, the presence of certain mosaic situations, small chromosomal abnormalities, discrepancies between tissues and contamination with maternal cells.
This report must be accompanied by the image of the corresponding karyotype and must be interpreted within the clinical context of the patient and according to medical criteria.

4. Methodology
             Cell culture. Identification by G bands (ISCN 2020) from two independent cultures. Resolution: 400-550 bands. Minimum number of metaphases analyzed: 20.

 5. Limitations and recommendations
             - The present result does not include the chromosomal findings interpreted as variants of normality (European Cytogeneticists Association (ECA) http://www.eca.eu/EN/GUIDELINES.html) and is subject to the limitations of this type of studies, such as, among others, the presence of certain situations in mosaic, chromosomal cryptic or small size anomalies, discrepancies between tissues and maternal contamination.
             - This report must be accompanied by the corresponding karyotype image and must be interpreted within the clinical context of the patient and according to medical criteria.

   Find the record of the test by clicking here