RISPERIDONE/ HYDROXIRISPERIDINE (SERUM)

Sample and Reference values Modification

Test code: 3417

Mnemonic code: RIPR

Effective update from 12/06/2023

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National: Sample: Frozen serum   Transoceanic: Sample: Frozen serum   Reference Values: Risperidone + Hidroxy-9-Risperidone *: 20 - 60 µg/L LOD  : 0.2 µg/L LOQ ): Risperidone: 1 µg/L  Hidroxi-9-Risperidone: 5 µg/L    *Hienke et Al (2018) Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology; update 2017. Pharmacopsychiatry;51;9-62.     Version of Test: 15

National: Sample: Refrigerated serum   Transoceanic: Sample: Frozen serum Therapeutic Range: Risperidone + Hidroxy-9-risperidone*: 20 - 60 μg/L *Range therapeutic according to European consensus AGNP-TDM Toxicity: Greater than 120 µg/L LoQ: Risperidone 1 μg/L Hidroxy-9-risperidone 5 μg/L   * Source: M. Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020   *Reminder about sample type: Send refrigerated / frozen serum sample as appropriate in tube without agar Version of Test: 16

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