Monday, June 24, 2024

NICKEL, URINE

Clarifications on Changes in Reference Values for Nickel in Urine

According to the new occupational regulations there is an update regarding the units of biological limit values for nickel.
Until now, the exposure index has been reported based on the calculation of nickel concentration with creatinine in urine (code 550 - NIQO), following the structure below:

Creatinine in urine at end of workday                       g/L
Nickel in urine at end of workday (concentration)     µg/L
Nickel in urine at end of workday                              µg/g

According to the ACGIH - American Conference of Governmental Industrial Hygienists, the biological exposure index for nickel in urine at the end of the workday is expressed in units of concentration, without considering the calculation with creatinine, as follows:

Nickel in urine at end of workday µg/L 
Exposure to elemental nickel and insoluble nickel compounds BEI (ACGIH) in urine at end of workweek: Less than 5 µg/L 
Exposure to soluble nickel compounds BEI (ACGIH) in urine at end of workweek: Less than 30 µg/L

Consequently, only the concentration value of nickel analyzed will be reported.

Mnemonic code, Results format and Reference values Modification


Test code: 550
Previous mnemonic code: NIQO
New mnemonic code: NIOC

Effective update from 01/07/2024




PREVIOUS

NEW
 Results format:
 R1 µg/g creatinine 
 R2 µg/L 

        
      B.E.I. (ACGIH 2022): after exposure to elemental Nickel and insoluble compounds: 5 µg/L
      B.E.I. (ACGIH 2022): after exposure to soluble compounds: 30 µg/L
      *B.E.I. - Biological Exposure Index.
      * Fuente: Valores Bibliograficos
     
      Version of Test: 14
     


 Results format:
 R1 µg/L 
         
         
Reference values:

Exposure to elemental nickel and insoluble nickel compounds:
BEI (ACGIH) in urine at end of workweek: Less than 5 µg/L
Exposure to soluble nickel compounds:
BEI (ACGIH) in urine at end of workweek: Less than 30 µg/L

Limit of quantification: 2 µg/L
  
     
      Version of Test: 15
     


   Find the record of the test by clicking here

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