IMIPRAMINE / DESIPRAMINE, SERUM

Reference values  Modification

Test code: 365

Mnemonic code: DESI

Effective update from 17/07/2023

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175-300 µg/L       Toxicity: >500 µg/L       Note: Imipramine is partially metabolised in desipramine, the sum of both being useful in therapeutic control. The therapeutic values that are indicated, refer to the aforementioned sum. The toxicity value corresponds to each drug individually.        * Fuente: PNT, Insert          Version of Test: 20

Therapeutic level: (Imipramine + Desipramine):  175  - 300 µg/L Toxicity: (Imipramine + Desipramine): Greater than 300 µg/L LoQ (Imipramine): 5 µg/L LoQ(Desipramine): 4 µg/L                              * Fuente: M. Schulz, A. Schmoldt, H. Andresen-Streichert, S. Iwersen-Bergmann. Revisited: Therapeutic and toxic blood concentrations of more than 1,100 drugs and other xenobiotics. Critical Care 2020                      Version of Test: 21

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