OXCARBAZEPINE + 10-OH CARBAZEPINE, SERUM

Reference values, Method and Delivery Time Modification

Test code: 7630

Mnemonic code: QOXC

Effective update from 17/07/2023

PREVIOUS

NEW

10-Hydroxycarbazepine : 5 - 30 mg/L Oxcarbazepine : 0.4 - 2 mg/L        LoQ 10-Hydroxycarbazepine: 1.0 mg/L LoQ Oxcarbazepine : 0.08 mg/L *NOTE: Oxcarbazepine is rapidly eliminated from serum, with an apparent half-life of 1.3 to 2.3 hours. * Source: PNT, Insert Method: Liquid Chromatography/Triple Quadrupole Mass Spectrometry       Delivery term: 6 days             Version of Test: 21

Therapeutic level:         10-Hydroxycarbazepine: 5 - 30 mg/L Oxcarbazepine: 0.4 - 2 mg/L Toxicity (10-Hydroxycarbazepine + Oxcarbazepine): Greater than 40 mg/L           LoQ 10-Hydroxycarbazepine: 1.0 mg/L LoQ Oxcarbazepine : 0.08 mg/L *NOTE: Oxcarbazepine is rapidly eliminated from serum, with an apparent half-life of 1.3 to 2.3 hours.                    * Source(Therapeutic level): PNT, Insert **Source (Toxicity): Hiemke C et al. Consensus Guidelines for Therapeutic drug monitoring Pharmacopsychiatry 2018; 51: 9–62. AGNP 2018. Method: Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)                              Delivery term: 5 days             Version of Test: 22

   Find the record of the test by clicking here